Kate Moss' sister Lottie Moss opens up about 'horrible' Ozempic overdose, hospitalization

Lottie Moss is opening up about her shocking struggles with Ozempic.

The British model, and sister to supermodel Kate Moss, got candid in a YouTube video on Thursday about past usage of the popular prescription drug which treats diabetes, obesity and heart disease.

"I'm not going to lie to you guys. I definitely tried it," Moss said in an episode of her "Dream On" podcast titled, “My Ozempic Hell: I Had Seizures, A&E, Weight Loss," calling her past use of Ozempic the "worst decision" she's ever made. She also told viewers she got the drug, which requires a prescription, from a friend and not a doctor.

"If this is a warning to anyone, please, if you’re thinking about doing it, do not take it," Moss, 26, told "Dream On" listeners. "Like, it’s so not worth it. I would rather die at any day than take that again."

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“I felt so sick one day, I said to my friend, ‘I can’t keep any water down. I can’t keep any food down, no liquids, nothing. I need to go to the hospital. I feel really sick,’” Lottie Moss said, recalling the incident.

Moss later had a seizure and called the situation the "scariest thing she's ever had to deal with" in her life and added that the incident was "honestly horrible."

She continued: "I hope by me talking about this and kind of saying my experience with it, it can be a lesson to some people that it's so not worth it."

"This should not be a trend right now, where did the body positivity go here? We were doing so well," she said, saying it's been going back to "super, super thin" body standards and calling the trend "heroin chic." Her sister Kate helped popularize a similar look in the 1990s during the rise of supermodel stardom.

She told fans to "be happy with your weight."

"It can be so detrimental in the future for your body. You don't realize it now, but restricting foods and things like that can really be so detrimental in the future," Moss said.

Moss said that when she was taking the drug, "the amount that I was taking was actually meant for people who are 100 kilos and over, and I'm in the 50s range." (100 kilos is 220 pounds while 50 kilos is roughly 110 pounds.)

Drugs such as Ozempic, Wegovy and Mounjaro can help someone lose 15% to 20% of their body weight – as much as 60 pounds for someone who started at 300.

Weight loss medications work by sending signals to the appetite center of the brain to reduce hunger and increase fullness, according to Dr. Deborah Horn, an assistant professor of surgery at the McGovern Medical School at UTHealth Houston. Once a person stops taking the drug, that effect is gone, paving the way for some people to regain what they lost if they don't adjust their diet and exercise patterns.

Side effects from Ozempic run the gamut – from losing too much weight, to gaining it all back, to plateauing. Not to mention the nausea, diarrhea and other gastrointestinal issues.

Contributing: David Oliver